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SOX5-SPSB2 Fusion FISH Probe

The SOX5-SPSB2 Fusion FISH Probe is used to confirm a fusion of the SOX5 and SPSB2 genes. The fusion of the SOX5 and SPSB2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SOX5-SPSB2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SOX5-SPSB2-20-RERE 20 (40 μL) 200 μL
SOX5-SPSB2-20-REOR 20 (40 μL) 200 μL
SOX5-SPSB2-20-REGO 20 (40 μL) 200 μL
SOX5-SPSB2-20-REGR 20 (40 μL) 200 μL
SOX5-SPSB2-20-REAQ 20 (40 μL) 200 μL
SOX5-SPSB2-20-ORRE 20 (40 μL) 200 μL
SOX5-SPSB2-20-OROR 20 (40 μL) 200 μL
SOX5-SPSB2-20-ORGO 20 (40 μL) 200 μL
SOX5-SPSB2-20-ORAQ 20 (40 μL) 200 μL
SOX5-SPSB2-20-GORE 20 (40 μL) 200 μL
SOX5-SPSB2-20-GOOR 20 (40 μL) 200 μL
SOX5-SPSB2-20-GOGO 20 (40 μL) 200 μL
SOX5-SPSB2-20-GOGR 20 (40 μL) 200 μL
SOX5-SPSB2-20-GOAQ 20 (40 μL) 200 μL
SOX5-SPSB2-20-GRRE 20 (40 μL) 200 μL
SOX5-SPSB2-20-GROR 20 (40 μL) 200 μL
SOX5-SPSB2-20-GRGO 20 (40 μL) 200 μL
SOX5-SPSB2-20-GRGR 20 (40 μL) 200 μL
SOX5-SPSB2-20-GRAQ 20 (40 μL) 200 μL
SOX5-SPSB2-20-AQRE 20 (40 μL) 200 μL
SOX5-SPSB2-20-AQOR 20 (40 μL) 200 μL
SOX5-SPSB2-20-AQGO 20 (40 μL) 200 μL
SOX5-SPSB2-20-AQGR 20 (40 μL) 200 μL
SOX5-SPSB2-20-AQAQ 20 (40 μL) 200 μL

SOX5 Gene Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Name: SRY-box 5

Chromosome: CHR12: 23685230 -24715380

Locus: 12p12.1

SPSB2 Gene Summary

This gene encodes a member of a subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal suppressor of cytokine signaling (SOCS) box. This protein plays a role in cell signaling. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Gene Name: SplA/ryanodine Receptor Domain And SOCS Box Containing 2

Chromosome: CHR12: 6980099 -6982521

Locus: 12p13.31

Gene Diseases

The SOX5 SPSB2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.