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SP1-ATF7 Fusion FISH Probe

The SP1-ATF7 Fusion FISH Probe is used to confirm a fusion of the SP1 and ATF7 genes. The fusion of the SP1 and ATF7 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SP1-ATF7-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SP1-ATF7-20-RERE 20 (40 μL) 200 μL
SP1-ATF7-20-REOR 20 (40 μL) 200 μL
SP1-ATF7-20-REGO 20 (40 μL) 200 μL
SP1-ATF7-20-REGR 20 (40 μL) 200 μL
SP1-ATF7-20-REAQ 20 (40 μL) 200 μL
SP1-ATF7-20-ORRE 20 (40 μL) 200 μL
SP1-ATF7-20-OROR 20 (40 μL) 200 μL
SP1-ATF7-20-ORGO 20 (40 μL) 200 μL
SP1-ATF7-20-ORAQ 20 (40 μL) 200 μL
SP1-ATF7-20-GORE 20 (40 μL) 200 μL
SP1-ATF7-20-GOOR 20 (40 μL) 200 μL
SP1-ATF7-20-GOGO 20 (40 μL) 200 μL
SP1-ATF7-20-GOGR 20 (40 μL) 200 μL
SP1-ATF7-20-GOAQ 20 (40 μL) 200 μL
SP1-ATF7-20-GRRE 20 (40 μL) 200 μL
SP1-ATF7-20-GROR 20 (40 μL) 200 μL
SP1-ATF7-20-GRGO 20 (40 μL) 200 μL
SP1-ATF7-20-GRGR 20 (40 μL) 200 μL
SP1-ATF7-20-GRAQ 20 (40 μL) 200 μL
SP1-ATF7-20-AQRE 20 (40 μL) 200 μL
SP1-ATF7-20-AQOR 20 (40 μL) 200 μL
SP1-ATF7-20-AQGO 20 (40 μL) 200 μL
SP1-ATF7-20-AQGR 20 (40 μL) 200 μL
SP1-ATF7-20-AQAQ 20 (40 μL) 200 μL

SP1 Gene Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Gene Name: Sp1 Transcription Factor

Chromosome: CHR12: 53773978 -53810226

Locus: 12q13.13

ATF7 Gene Summary

The Activating Transcription Factor 7 (ATF7) gene is located on chr12 :53905842-54020199 at 12q13.13.

Gene Name: Activating Transcription Factor 7

Chromosome: CHR12: 53905842 -54020199

Locus: 12q13.13

Gene Diseases

The SP1 ATF7 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.