SPOCK1-CDC23 Fusion FISH Probe
The SPOCK1-CDC23 Fusion FISH Probe is used to confirm a fusion of the SPOCK1 and CDC23 genes. The fusion of the SPOCK1 and CDC23 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPOCK1-CDC23-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-RERE | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-REOR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-REGO | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-REGR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-REAQ | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-ORRE | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-OROR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-ORGO | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GORE | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GOOR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GOGO | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GOGR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GRRE | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GROR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GRGO | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GRGR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-AQRE | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-AQOR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-AQGO | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-AQGR | 20 (40 μL) | 200 μL |
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| SPOCK1-CDC23-20-AQAQ | 20 (40 μL) | 200 μL |
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SPOCK1 Gene Summary
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]
Gene Name: SPARC/osteonectin, Cwcv And Kazal Like Domains Proteoglycan 1
Chromosome: CHR5: 136310986 -136835018
Locus: 5q31.2
CDC23 Gene Summary
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]
Gene Name: Cell Division Cycle 23
Chromosome: CHR5: 137523336 -137549032
Locus: 5q31.2
Gene Diseases
The SPOCK1 CDC23 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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