SPRED1-GANC Fusion FISH Probe
The SPRED1-GANC Fusion FISH Probe is used to confirm a fusion of the SPRED1 and GANC genes. The fusion of the SPRED1 and GANC genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPRED1-GANC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-RERE | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-REOR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-REGO | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-REGR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-REAQ | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-ORRE | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-OROR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-ORGO | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GORE | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GOOR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GOGO | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GOGR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GRRE | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GROR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GRGO | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GRGR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-AQRE | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-AQOR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-AQGO | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-AQGR | 20 (40 μL) | 200 μL |
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| SPRED1-GANC-20-AQAQ | 20 (40 μL) | 200 μL |
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GANC Gene Summary
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]
Gene Name: Glucosidase Alpha, Neutral C
Chromosome: CHR15: 42566365 -42645864
Locus: 15q15.1
SPRED1 Gene Summary
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]
Gene Name: Sprouty Related EVH1 Domain Containing 1
Chromosome: CHR15: 38545051 -38649450
Locus: 15q14
Gene Diseases
The SPRED1 GANC Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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