SPTBN1-STX8 Fusion FISH Probe
The SPTBN1-STX8 Fusion FISH Probe is used to confirm a fusion of the SPTBN1 and STX8 genes. The fusion of the SPTBN1 and STX8 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SPTBN1-STX8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-RERE | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-REOR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-REGO | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-REGR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-REAQ | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-ORRE | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-OROR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-ORGO | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-ORAQ | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GORE | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GOOR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GOGO | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GOGR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GOAQ | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GRRE | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GROR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GRGO | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GRGR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-GRAQ | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-AQRE | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-AQOR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-AQGO | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-AQGR | 20 (40 μL) | 200 μL |
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| SPTBN1-STX8-20-AQAQ | 20 (40 μL) | 200 μL |
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SPTBN1 Gene Summary
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Spectrin Beta, Non-erythrocytic 1
Chromosome: CHR2: 54683453 -54898583
Locus: 2p16.2
STX8 Gene Summary
The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Name: Syntaxin 8
Chromosome: CHR17: 9153787 -9479275
Locus: 17p13.1
Gene Diseases
The SPTBN1 STX8 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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