SQSTM1-GRIA1 Fusion FISH Probe
The SQSTM1-GRIA1 Fusion FISH Probe is used to confirm a fusion of the SQSTM1 and GRIA1 genes. The fusion of the SQSTM1 and GRIA1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SQSTM1-GRIA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-RERE | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-REOR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-REGO | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-REGR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-REAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-ORRE | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-OROR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-ORGO | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GORE | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GOOR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GOGO | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GOGR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GRRE | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GROR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GRGO | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GRGR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-AQRE | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-AQOR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-AQGO | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-AQGR | 20 (40 μL) | 200 μL |
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| SQSTM1-GRIA1-20-AQAQ | 20 (40 μL) | 200 μL |
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GRIA1 Gene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Glutamate Ionotropic Receptor AMPA Type Subunit 1
Chromosome: CHR5: 152870083 -153193429
Locus: 5q33.2
SQSTM1 Gene Summary
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Gene Name: Sequestosome 1
Chromosome: CHR5: 179233387 -179265077
Locus: 5q35.3
Gene Diseases
The SQSTM1 GRIA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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