SQSTM1-NTRK1 Fusion FISH Probe
The SQSTM1-NTRK1 Fusion FISH Probe is used to confirm a fusion of the SQSTM1 and NTRK1 genes. The fusion of the SQSTM1 and NTRK1 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SQSTM1-NTRK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-RERE | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-REOR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-REGO | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-REGR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-REAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-ORRE | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-OROR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-ORGO | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GORE | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GOOR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GOGO | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GOGR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GRRE | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GROR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GRGO | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GRGR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-AQRE | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-AQOR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-AQGO | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-AQGR | 20 (40 μL) | 200 μL |
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| SQSTM1-NTRK1-20-AQAQ | 20 (40 μL) | 200 μL |
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NTRK1 Gene Summary
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Gene Name: Neurotrophic Receptor Tyrosine Kinase 1
Chromosome: CHR1: 156785541 -156851642
Locus: 1q23.1
SQSTM1 Gene Summary
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Gene Name: Sequestosome 1
Chromosome: CHR5: 179233387 -179265077
Locus: 5q35.3
Gene Diseases
The SQSTM1 NTRK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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