SRD5A1-ADAMTS16 Fusion FISH Probe
The SRD5A1-ADAMTS16 Fusion FISH Probe is used to confirm a fusion of the SRD5A1 and ADAMTS16 genes. The fusion of the SRD5A1 and ADAMTS16 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SRD5A1-ADAMTS16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-RERE | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-REOR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-REGO | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-REGR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-REAQ | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-ORRE | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-OROR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-ORGO | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-ORAQ | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GORE | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GOOR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GOGO | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GOGR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GOAQ | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GRRE | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GROR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GRGO | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GRGR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-GRAQ | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-AQRE | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-AQOR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-AQGO | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-AQGR | 20 (40 μL) | 200 μL |
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| SRD5A1-ADAMTS16-20-AQAQ | 20 (40 μL) | 200 μL |
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SRD5A1 Gene Summary
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
Gene Name: Steroid 5 Alpha-reductase 1
Chromosome: CHR5: 6633499 -6669675
Locus: 5p15.31
ADAMTS16 Gene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure. [provided by RefSeq, May 2016]
Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 16
Chromosome: CHR5: 5140442 -5320412
Locus: 5p15.32
Gene Diseases
The SRD5A1 ADAMTS16 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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