SRGAP1-BACE2 Fusion FISH Probe
The SRGAP1-BACE2 Fusion FISH Probe is used to confirm a fusion of the SRGAP1 and BACE2 genes. The fusion of the SRGAP1 and BACE2 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SRGAP1-BACE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-RERE | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-REOR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-REGO | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-REGR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-REAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-ORRE | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-OROR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-ORGO | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GORE | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GOOR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GOGO | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GOGR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GRRE | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GROR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GRGO | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GRGR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-AQRE | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-AQOR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-AQGO | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-AQGR | 20 (40 μL) | 200 μL |
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| SRGAP1-BACE2-20-AQAQ | 20 (40 μL) | 200 μL |
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BACE2 Gene Summary
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: Beta-site APP-cleaving Enzyme 2
Chromosome: CHR21: 42539727 -42648524
Locus: 21q22.2-q22.3
SRGAP1 Gene Summary
The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]
Gene Name: SLIT-ROBO Rho GTPase Activating Protein 1
Chromosome: CHR12: 64238540 -64541613
Locus: 12q14.2
Gene Diseases
The SRGAP1 BACE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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