SRP68-EXOC7 Fusion FISH Probe
The SRP68-EXOC7 Fusion FISH Probe is used to confirm a fusion of the SRP68 and EXOC7 genes. The fusion of the SRP68 and EXOC7 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SRP68-EXOC7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-RERE | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-REOR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-REGO | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-REGR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-REAQ | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-ORRE | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-OROR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-ORGO | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-ORAQ | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GORE | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GOOR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GOGO | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GOGR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GOAQ | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GRRE | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GROR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GRGO | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GRGR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-GRAQ | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-AQRE | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-AQOR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-AQGO | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-AQGR | 20 (40 μL) | 200 μL |
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| SRP68-EXOC7-20-AQAQ | 20 (40 μL) | 200 μL |
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SRP68 Gene Summary
This gene encodes a subunit of the signal recognition particle (SRP). The SRP is a ribonucleoprotein complex that transports secreted and membrane proteins to the endoplasmic reticulum for processing. The complex includes a 7S RNA and six protein subunits. The encoded protein is the 68kDa component of the SRP, and forms a heterodimer with the 72kDa subunit that is required for SRP function. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and three pseudogenes of this gene are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, May 2012]
Gene Name: Signal Recognition Particle 68
Chromosome: CHR17: 74035190 -74068607
Locus: 17q25.1
EXOC7 Gene Summary
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]
Gene Name: Exocyst Complex Component 7
Chromosome: CHR17: 74077085 -74099868
Locus: 17q25.1
Gene Diseases
The SRP68 EXOC7 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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