ST5-TMEM9B Fusion FISH Probe
The ST5-TMEM9B Fusion FISH Probe is used to confirm a fusion of the ST5 and TMEM9B genes. The fusion of the ST5 and TMEM9B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ST5-TMEM9B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-RERE | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-REOR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-REGO | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-REGR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-REAQ | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-ORRE | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-OROR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-ORGO | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GORE | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GOOR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GOGO | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GOGR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GRRE | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GROR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GRGO | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GRGR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-AQRE | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-AQOR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-AQGO | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-AQGR | 20 (40 μL) | 200 μL |
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| ST5-TMEM9B-20-AQAQ | 20 (40 μL) | 200 μL |
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ST5 Gene Summary
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008]
Gene Name: Suppression Of Tumorigenicity 5
Chromosome: CHR11: 8714898 -8932498
Locus: 11p15.4
TMEM9B Gene Summary
The TMEM9 Domain Family Member B (TMEM9B) gene is located on chr11 :8968839-8985989 at 11p15.4.
Gene Name: TMEM9 Domain Family Member B
Chromosome: CHR11: 8968839 -8985989
Locus: 11p15.4
Gene Diseases
The ST5 TMEM9B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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