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ST7-CAV1 Fusion FISH Probe

The ST7-CAV1 Fusion FISH Probe is used to confirm a fusion of the ST7 and CAV1 genes. The fusion of the ST7 and CAV1 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ST7-CAV1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ST7-CAV1-20-RERE 20 (40 μL) 200 μL
ST7-CAV1-20-REOR 20 (40 μL) 200 μL
ST7-CAV1-20-REGO 20 (40 μL) 200 μL
ST7-CAV1-20-REGR 20 (40 μL) 200 μL
ST7-CAV1-20-REAQ 20 (40 μL) 200 μL
ST7-CAV1-20-ORRE 20 (40 μL) 200 μL
ST7-CAV1-20-OROR 20 (40 μL) 200 μL
ST7-CAV1-20-ORGO 20 (40 μL) 200 μL
ST7-CAV1-20-ORAQ 20 (40 μL) 200 μL
ST7-CAV1-20-GORE 20 (40 μL) 200 μL
ST7-CAV1-20-GOOR 20 (40 μL) 200 μL
ST7-CAV1-20-GOGO 20 (40 μL) 200 μL
ST7-CAV1-20-GOGR 20 (40 μL) 200 μL
ST7-CAV1-20-GOAQ 20 (40 μL) 200 μL
ST7-CAV1-20-GRRE 20 (40 μL) 200 μL
ST7-CAV1-20-GROR 20 (40 μL) 200 μL
ST7-CAV1-20-GRGO 20 (40 μL) 200 μL
ST7-CAV1-20-GRGR 20 (40 μL) 200 μL
ST7-CAV1-20-GRAQ 20 (40 μL) 200 μL
ST7-CAV1-20-AQRE 20 (40 μL) 200 μL
ST7-CAV1-20-AQOR 20 (40 μL) 200 μL
ST7-CAV1-20-AQGO 20 (40 μL) 200 μL
ST7-CAV1-20-AQGR 20 (40 μL) 200 μL
ST7-CAV1-20-AQAQ 20 (40 μL) 200 μL

CAV1 Gene Summary

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]

Gene Name: Caveolin 1

Chromosome: CHR7: 116164838 -116201239

Locus: 7q31.2

ST7 Gene Summary

The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]

Gene Name: Suppression Of Tumorigenicity 7

Chromosome: CHR7: 116593380 -116870075

Locus: 7q31.2

Gene Diseases

The ST7 CAV1 Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.