ST7-TBXAS1 Fusion FISH Probe
The ST7-TBXAS1 Fusion FISH Probe is used to confirm a fusion of the ST7 and TBXAS1 genes. The fusion of the ST7 and TBXAS1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ST7-TBXAS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-RERE | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-REOR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-REGO | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-REGR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-REAQ | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-ORRE | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-OROR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-ORGO | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GORE | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GOOR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GOGO | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GOGR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GRRE | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GROR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GRGO | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GRGR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-AQRE | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-AQOR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-AQGO | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-AQGR | 20 (40 μL) | 200 μL |
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| ST7-TBXAS1-20-AQAQ | 20 (40 μL) | 200 μL |
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TBXAS1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Thromboxane A Synthase 1
Chromosome: CHR7: 139478046 -139720125
Locus: 7q34
ST7 Gene Summary
The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: Suppression Of Tumorigenicity 7
Chromosome: CHR7: 116593380 -116870075
Locus: 7q31.2
Gene Diseases
The ST7 TBXAS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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