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STAT3-ETV4 Fusion FISH Probe

The STAT3-ETV4 Fusion FISH Probe is used to confirm a fusion of the STAT3 and ETV4 genes. The fusion of the STAT3 and ETV4 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
STAT3-ETV4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
STAT3-ETV4-20-RERE 20 (40 μL) 200 μL
STAT3-ETV4-20-REOR 20 (40 μL) 200 μL
STAT3-ETV4-20-REGO 20 (40 μL) 200 μL
STAT3-ETV4-20-REGR 20 (40 μL) 200 μL
STAT3-ETV4-20-REAQ 20 (40 μL) 200 μL
STAT3-ETV4-20-ORRE 20 (40 μL) 200 μL
STAT3-ETV4-20-OROR 20 (40 μL) 200 μL
STAT3-ETV4-20-ORGO 20 (40 μL) 200 μL
STAT3-ETV4-20-ORAQ 20 (40 μL) 200 μL
STAT3-ETV4-20-GORE 20 (40 μL) 200 μL
STAT3-ETV4-20-GOOR 20 (40 μL) 200 μL
STAT3-ETV4-20-GOGO 20 (40 μL) 200 μL
STAT3-ETV4-20-GOGR 20 (40 μL) 200 μL
STAT3-ETV4-20-GOAQ 20 (40 μL) 200 μL
STAT3-ETV4-20-GRRE 20 (40 μL) 200 μL
STAT3-ETV4-20-GROR 20 (40 μL) 200 μL
STAT3-ETV4-20-GRGO 20 (40 μL) 200 μL
STAT3-ETV4-20-GRGR 20 (40 μL) 200 μL
STAT3-ETV4-20-GRAQ 20 (40 μL) 200 μL
STAT3-ETV4-20-AQRE 20 (40 μL) 200 μL
STAT3-ETV4-20-AQOR 20 (40 μL) 200 μL
STAT3-ETV4-20-AQGO 20 (40 μL) 200 μL
STAT3-ETV4-20-AQGR 20 (40 μL) 200 μL
STAT3-ETV4-20-AQAQ 20 (40 μL) 200 μL

ETV4 Gene Summary

The ETS Variant 4 (ETV4) gene is located on chr17 :41605210-41623762 at 17q21.31.

Gene Name: ETS Variant 4

Chromosome: CHR17: 41605210 -41623762

Locus: 17q21.31

STAT3 Gene Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]

Gene Name: Signal Transducer And Activator Of Transcription 3

Chromosome: CHR17: 40465342 -40540513

Locus: 17q21.2

Gene Diseases

The STAT3 ETV4 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.