STAT5B-ODZ4 Fusion FISH Probe
The STAT5B-ODZ4 Fusion FISH Probe is used to confirm a fusion of the STAT5B and ODZ4 genes. The fusion of the STAT5B and ODZ4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STAT5B-ODZ4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-RERE | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-REOR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-REGO | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-REGR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-REAQ | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-ORRE | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-OROR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-ORGO | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-ORAQ | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GORE | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GOOR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GOGO | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GOGR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GOAQ | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GRRE | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GROR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GRGO | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GRGR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-GRAQ | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-AQRE | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-AQOR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-AQGO | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-AQGR | 20 (40 μL) | 200 μL |
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| STAT5B-ODZ4-20-AQAQ | 20 (40 μL) | 200 μL |
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STAT5B Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
Gene Name: Signal Transducer And Activator Of Transcription 5B
Chromosome: CHR17: 40351194 -40428424
Locus: 17q21.2
Gene Diseases
The STAT5B ODZ4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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