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STIM1-FITM2 Fusion FISH Probe

The STIM1-FITM2 Fusion FISH Probe is used to confirm a fusion of the STIM1 and FITM2 genes. The fusion of the STIM1 and FITM2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
STIM1-FITM2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
STIM1-FITM2-20-RERE 20 (40 μL) 200 μL
STIM1-FITM2-20-REOR 20 (40 μL) 200 μL
STIM1-FITM2-20-REGO 20 (40 μL) 200 μL
STIM1-FITM2-20-REGR 20 (40 μL) 200 μL
STIM1-FITM2-20-REAQ 20 (40 μL) 200 μL
STIM1-FITM2-20-ORRE 20 (40 μL) 200 μL
STIM1-FITM2-20-OROR 20 (40 μL) 200 μL
STIM1-FITM2-20-ORGO 20 (40 μL) 200 μL
STIM1-FITM2-20-ORAQ 20 (40 μL) 200 μL
STIM1-FITM2-20-GORE 20 (40 μL) 200 μL
STIM1-FITM2-20-GOOR 20 (40 μL) 200 μL
STIM1-FITM2-20-GOGO 20 (40 μL) 200 μL
STIM1-FITM2-20-GOGR 20 (40 μL) 200 μL
STIM1-FITM2-20-GOAQ 20 (40 μL) 200 μL
STIM1-FITM2-20-GRRE 20 (40 μL) 200 μL
STIM1-FITM2-20-GROR 20 (40 μL) 200 μL
STIM1-FITM2-20-GRGO 20 (40 μL) 200 μL
STIM1-FITM2-20-GRGR 20 (40 μL) 200 μL
STIM1-FITM2-20-GRAQ 20 (40 μL) 200 μL
STIM1-FITM2-20-AQRE 20 (40 μL) 200 μL
STIM1-FITM2-20-AQOR 20 (40 μL) 200 μL
STIM1-FITM2-20-AQGO 20 (40 μL) 200 μL
STIM1-FITM2-20-AQGR 20 (40 μL) 200 μL
STIM1-FITM2-20-AQAQ 20 (40 μL) 200 μL

STIM1 Gene Summary

This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Gene Name: Stromal Interaction Molecule 1

Chromosome: CHR11: 3876932 -4114440

Locus: 11p15.4

FITM2 Gene Summary

FIT2 belongs to an evolutionarily conserved family of proteins involved in fat storage (Kadereit et al., 2008 [PubMed 18160536]).[supplied by OMIM, May 2008]

Gene Name: Fat Storage Inducing Transmembrane Protein 2

Chromosome: CHR20: 42935196 -42939889

Locus: 20q13.12

Gene Diseases

The STIM1 FITM2 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.