STK3-SLC26A7 Fusion FISH Probe
The STK3-SLC26A7 Fusion FISH Probe is used to confirm a fusion of the STK3 and SLC26A7 genes. The fusion of the STK3 and SLC26A7 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STK3-SLC26A7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-RERE | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-REOR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-REGO | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-REGR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-REAQ | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-ORRE | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-OROR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-ORGO | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-ORAQ | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GORE | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GOOR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GOGO | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GOGR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GOAQ | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GRRE | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GROR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GRGO | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GRGR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-GRAQ | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-AQRE | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-AQOR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-AQGO | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-AQGR | 20 (40 μL) | 200 μL |
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| STK3-SLC26A7-20-AQAQ | 20 (40 μL) | 200 μL |
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STK3 Gene Summary
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Serine/threonine Kinase 3
Chromosome: CHR8: 99466860 -99837909
Locus: 8q22.2
SLC26A7 Gene Summary
This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. This gene has abundant and specific expression in the kidney. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Aug 2013]
Gene Name: Solute Carrier Family 26 Member 7
Chromosome: CHR8: 92261515 -92410378
Locus: 8q21.3
Gene Diseases
The STK3 SLC26A7 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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