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STRBP-DENND1A Fusion FISH Probe

The STRBP-DENND1A Fusion FISH Probe is used to confirm a fusion of the STRBP and DENND1A genes. The fusion of the STRBP and DENND1A genes has been associated with Lung Squamous Cell Carcinoma, Stomach Adenocarcinoma, Uterine Corpus Endometrial Carcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
STRBP-DENND1A-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
STRBP-DENND1A-20-RERE 20 (40 μL) 200 μL
STRBP-DENND1A-20-REOR 20 (40 μL) 200 μL
STRBP-DENND1A-20-REGO 20 (40 μL) 200 μL
STRBP-DENND1A-20-REGR 20 (40 μL) 200 μL
STRBP-DENND1A-20-REAQ 20 (40 μL) 200 μL
STRBP-DENND1A-20-ORRE 20 (40 μL) 200 μL
STRBP-DENND1A-20-OROR 20 (40 μL) 200 μL
STRBP-DENND1A-20-ORGO 20 (40 μL) 200 μL
STRBP-DENND1A-20-ORAQ 20 (40 μL) 200 μL
STRBP-DENND1A-20-GORE 20 (40 μL) 200 μL
STRBP-DENND1A-20-GOOR 20 (40 μL) 200 μL
STRBP-DENND1A-20-GOGO 20 (40 μL) 200 μL
STRBP-DENND1A-20-GOGR 20 (40 μL) 200 μL
STRBP-DENND1A-20-GOAQ 20 (40 μL) 200 μL
STRBP-DENND1A-20-GRRE 20 (40 μL) 200 μL
STRBP-DENND1A-20-GROR 20 (40 μL) 200 μL
STRBP-DENND1A-20-GRGO 20 (40 μL) 200 μL
STRBP-DENND1A-20-GRGR 20 (40 μL) 200 μL
STRBP-DENND1A-20-GRAQ 20 (40 μL) 200 μL
STRBP-DENND1A-20-AQRE 20 (40 μL) 200 μL
STRBP-DENND1A-20-AQOR 20 (40 μL) 200 μL
STRBP-DENND1A-20-AQGO 20 (40 μL) 200 μL
STRBP-DENND1A-20-AQGR 20 (40 μL) 200 μL
STRBP-DENND1A-20-AQAQ 20 (40 μL) 200 μL

STRBP Gene Summary

The Spermatid Perinuclear RNA Binding Protein (STRBP) gene is located on chr9 :125883907-126030855 at 9q33.3.

Gene Name: Spermatid Perinuclear RNA Binding Protein

Chromosome: CHR9: 125883907 -126030855

Locus: 9q33.3

DENND1A Gene Summary

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]

Gene Name: DENN Domain Containing 1A

Chromosome: CHR9: 126141932 -126692417

Locus: 9q33.3

Gene Diseases

The STRBP DENND1A Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma
Stomach Adenocarcinoma
Uterine Corpus Endometrial Carcinoma
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.