STX5-ASIP Fusion FISH Probe
The STX5-ASIP Fusion FISH Probe is used to confirm a fusion of the STX5 and ASIP genes. The fusion of the STX5 and ASIP genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STX5-ASIP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-RERE | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-REOR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-REGO | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-REGR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-REAQ | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-ORRE | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-OROR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-ORGO | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-ORAQ | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GORE | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GOOR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GOGO | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GOGR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GOAQ | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GRRE | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GROR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GRGO | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GRGR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-GRAQ | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-AQRE | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-AQOR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-AQGO | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-AQGR | 20 (40 μL) | 200 μL |
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| STX5-ASIP-20-AQAQ | 20 (40 μL) | 200 μL |
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ASIP Gene Summary
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes. [provided by RefSeq, Jul 2008]
Gene Name: Agouti Signaling Protein
Chromosome: CHR20: 32848170 -32857148
Locus: 20q11.22
STX5 Gene Summary
This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Syntaxin 5
Chromosome: CHR11: 62574368 -62599560
Locus: 11q12.3
Gene Diseases
The STX5 ASIP Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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