STX7-LMBRD1 Fusion FISH Probe
The STX7-LMBRD1 Fusion FISH Probe is used to confirm a fusion of the STX7 and LMBRD1 genes. The fusion of the STX7 and LMBRD1 genes has been associated with Uveal Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STX7-LMBRD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-RERE | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-REOR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-REGO | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-REGR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-REAQ | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-ORRE | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-OROR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-ORGO | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GORE | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GOOR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GOGO | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GOGR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GRRE | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GROR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GRGO | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GRGR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-AQRE | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-AQOR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-AQGO | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-AQGR | 20 (40 μL) | 200 μL |
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| STX7-LMBRD1-20-AQAQ | 20 (40 μL) | 200 μL |
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STX7 Gene Summary
The protein encoded by this gene is a syntaxin family membrane receptor involved in vesicle transport. The encoded protein binds alpha-SNAP, an important regulator of transport vesicle fusion. Along with syntaxin 13, this protein plays a role in the ordered fusion of endosomes and lysosomes with the phagosome. [provided by RefSeq, May 2016]
Gene Name: Syntaxin 7
Chromosome: CHR6: 132778662 -132834337
Locus: 6q23.2
LMBRD1 Gene Summary
This gene encodes a lysosomal membrane protein that may be involved in the transport and metabolism of cobalamin. This protein also interacts with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F.[provided by RefSeq, Oct 2009]
Gene Name: LMBR1 Domain Containing 1
Chromosome: CHR6: 70385640 -70507049
Locus: 6q13
Gene Diseases
The STX7 LMBRD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uveal Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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