STYX-DAD1 Fusion FISH Probe
The STYX-DAD1 Fusion FISH Probe is used to confirm a fusion of the STYX and DAD1 genes. The fusion of the STYX and DAD1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| STYX-DAD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-RERE | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-REOR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-REGO | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-REGR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-REAQ | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-ORRE | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-OROR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-ORGO | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GORE | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GOOR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GOGO | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GOGR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GRRE | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GROR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GRGO | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GRGR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-AQRE | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-AQOR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-AQGO | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-AQGR | 20 (40 μL) | 200 μL |
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| STYX-DAD1-20-AQAQ | 20 (40 μL) | 200 μL |
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DAD1 Gene Summary
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008]
Gene Name: Defender Against Cell Death 1
Chromosome: CHR14: 23033806 -23058143
Locus: 14q11.2
STYX Gene Summary
The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for these genes. [provided by RefSeq, Oct 2011]
Gene Name: Serine/threonine/tyrosine Interacting Protein
Chromosome: CHR14: 53196882 -53241705
Locus: 14q22.1
Gene Diseases
The STYX DAD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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