SUFU-CYP26A1 Fusion FISH Probe
The SUFU-CYP26A1 Fusion FISH Probe is used to confirm a fusion of the SUFU and CYP26A1 genes. The fusion of the SUFU and CYP26A1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SUFU-CYP26A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-RERE | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-REOR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-REGO | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-REGR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-REAQ | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-ORRE | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-OROR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-ORGO | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GORE | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GOOR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GOGO | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GOGR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GRRE | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GROR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GRGO | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GRGR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-AQRE | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-AQOR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-AQGO | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-AQGR | 20 (40 μL) | 200 μL |
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| SUFU-CYP26A1-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP26A1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 26 Subfamily A Member 1
Chromosome: CHR10: 94833231 -94837641
Locus: 10q23.33
SUFU Gene Summary
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: SUFU Negative Regulator Of Hedgehog Signaling
Chromosome: CHR10: 104263718 -104393214
Locus: 10q24.32
Gene Diseases
The SUFU CYP26A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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