SUFU-GBF1 Fusion FISH Probe
The SUFU-GBF1 Fusion FISH Probe is used to confirm a fusion of the SUFU and GBF1 genes. The fusion of the SUFU and GBF1 genes has been associated with Uterine Corpus Endometrial Carcinoma, Breast Invasive Carcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SUFU-GBF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SUFU-GBF1-20-AQAQ | 20 (40 μL) | 200 μL |
|
GBF1 Gene Summary
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Golgi Brefeldin A Resistant Guanine Nucleotide Exchange Factor 1
Chromosome: CHR10: 104005254 -104142656
Locus: 10q24.32
SUFU Gene Summary
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: SUFU Negative Regulator Of Hedgehog Signaling
Chromosome: CHR10: 104263718 -104393214
Locus: 10q24.32
Gene Diseases
The SUFU GBF1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
| Breast Invasive Carcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|