SULF2-TSHZ2 Fusion FISH Probe
The SULF2-TSHZ2 Fusion FISH Probe is used to confirm a fusion of the SULF2 and TSHZ2 genes. The fusion of the SULF2 and TSHZ2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SULF2-TSHZ2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-RERE | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-REOR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-REGO | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-REGR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-REAQ | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-ORRE | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-OROR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-ORGO | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GORE | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GOOR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GOGO | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GOGR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GRRE | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GROR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GRGO | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GRGR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-AQRE | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-AQOR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-AQGO | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-AQGR | 20 (40 μL) | 200 μL |
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| SULF2-TSHZ2-20-AQAQ | 20 (40 μL) | 200 μL |
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SULF2 Gene Summary
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
Gene Name: Sulfatase 2
Chromosome: CHR20: 46286149 -46415360
Locus: 20q13.12
TSHZ2 Gene Summary
This gene is a member of the teashirt C2H2-type zinc-finger protein family of transcription factors. This gene encodes a protein with five C2H2-type zinc fingers, a homeobox DNA-binding domain and a coiled-coil domain. This nuclear protein is predicted to act as a transcriptional repressor. This gene is thought to play a role in the development and progression of breast and other types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Name: Teashirt Zinc Finger Homeobox 2
Chromosome: CHR20: 51588945 -52111869
Locus: 20q13.2
Gene Diseases
The SULF2 TSHZ2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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