TAF13-LYPLA1 Fusion FISH Probe
The TAF13-LYPLA1 Fusion FISH Probe is used to confirm a fusion of the TAF13 and LYPLA1 genes. The fusion of the TAF13 and LYPLA1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TAF13-LYPLA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-RERE | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-REOR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-REGO | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-REGR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-REAQ | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-ORRE | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-OROR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-ORGO | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GORE | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GOOR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GOGO | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GOGR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GRRE | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GROR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GRGO | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GRGR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-AQRE | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-AQOR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-AQGO | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-AQGR | 20 (40 μL) | 200 μL |
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| TAF13-LYPLA1-20-AQAQ | 20 (40 μL) | 200 μL |
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TAF13 Gene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6. [provided by RefSeq, Jul 2008]
Gene Name: TATA-box Binding Protein Associated Factor 13
Chromosome: CHR1: 109606997 -109618624
Locus: 1p13.3
LYPLA1 Gene Summary
This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013]
Gene Name: Lysophospholipase I
Chromosome: CHR8: 54958937 -55014577
Locus: 8q11.23
Gene Diseases
The TAF13 LYPLA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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