TAF3-ATP5C1 Fusion FISH Probe
The TAF3-ATP5C1 Fusion FISH Probe is used to confirm a fusion of the TAF3 and ATP5C1 genes. The fusion of the TAF3 and ATP5C1 genes has been associated with Lung Adenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TAF3-ATP5C1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-RERE | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-REOR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-REGO | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-REGR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-REAQ | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-ORRE | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-OROR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-ORGO | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GORE | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GOOR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GOGO | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GOGR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GRRE | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GROR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GRGO | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GRGR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-AQRE | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-AQOR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-AQGO | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-AQGR | 20 (40 μL) | 200 μL |
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| TAF3-ATP5C1-20-AQAQ | 20 (40 μL) | 200 μL |
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ATP5C1 Gene Summary
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq, Jul 2008]
Gene Name: ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Gamma Polypeptide 1
Chromosome: CHR10: 7830092 -7849762
Locus: 10p14
TAF3 Gene Summary
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009]
Gene Name: TATA-box Binding Protein Associated Factor 3
Chromosome: CHR10: 7860672 -8056714
Locus: 10p14
Gene Diseases
The TAF3 ATP5C1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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