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TAX1BP1-CHN2 Fusion FISH Probe

The TAX1BP1-CHN2 Fusion FISH Probe is used to confirm a fusion of the TAX1BP1 and CHN2 genes. The fusion of the TAX1BP1 and CHN2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TAX1BP1-CHN2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-RERE 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-REOR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-REGO 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-REGR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-REAQ 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-ORRE 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-OROR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-ORGO 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-ORAQ 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GORE 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GOOR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GOGO 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GOGR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GOAQ 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GRRE 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GROR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GRGO 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GRGR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-GRAQ 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-AQRE 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-AQOR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-AQGO 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-AQGR 20 (40 μL) 200 μL
TAX1BP1-CHN2-20-AQAQ 20 (40 μL) 200 μL

CHN2 Gene Summary

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]

Gene Name: Chimerin 2

Chromosome: CHR7: 29234120 -29553944

Locus: 7p14.3

TAX1BP1 Gene Summary

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

Gene Name: Tax1 Binding Protein 1

Chromosome: CHR7: 27778991 -27869386

Locus: 7p15.2

Gene Diseases

The TAX1BP1 CHN2 Fusion has been associated with the following diseases:

Disease Name
Esophageal Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.