TBX15-AP4B1 Fusion FISH Probe
The TBX15-AP4B1 Fusion FISH Probe is used to confirm a fusion of the TBX15 and AP4B1 genes. The fusion of the TBX15 and AP4B1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TBX15-AP4B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-RERE | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-REOR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-REGO | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-REGR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-REAQ | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-ORRE | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-OROR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-ORGO | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GORE | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GOOR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GOGO | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GOGR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GRRE | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GROR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GRGO | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GRGR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-AQRE | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-AQOR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-AQGO | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-AQGR | 20 (40 μL) | 200 μL |
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| TBX15-AP4B1-20-AQAQ | 20 (40 μL) | 200 μL |
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TBX15 Gene Summary
This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009]
Gene Name: T-box 15
Chromosome: CHR1: 119425665 -119532179
Locus: 1p12
AP4B1 Gene Summary
This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Adaptor Related Protein Complex 4 Beta 1 Subunit
Chromosome: CHR1: 114437676 -114447741
Locus: 1p13.2
Gene Diseases
The TBX15 AP4B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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