TCF25-SPIRE2 Fusion FISH Probe
The TCF25-SPIRE2 Fusion FISH Probe is used to confirm a fusion of the TCF25 and SPIRE2 genes. The fusion of the TCF25 and SPIRE2 genes has been associated with Lung Adenocarcinoma, Breast Invasive Carcinoma, and Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TCF25-SPIRE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-RERE | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-REOR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-REGO | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-REGR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-REAQ | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-ORRE | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-OROR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-ORGO | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GORE | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GOOR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GOGO | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GOGR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GRRE | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GROR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GRGO | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GRGR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-AQRE | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-AQOR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-AQGO | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-AQGR | 20 (40 μL) | 200 μL |
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| TCF25-SPIRE2-20-AQAQ | 20 (40 μL) | 200 μL |
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TCF25 Gene Summary
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008]
Gene Name: Transcription Factor 25
Chromosome: CHR16: 89939993 -89977792
Locus: 16q24.3
SPIRE2 Gene Summary
The Spire Type Actin Nucleation Factor 2 (SPIRE2) gene is located on chr16 :89894906-89937727 at 16q24.3.
Gene Name: Spire Type Actin Nucleation Factor 2
Chromosome: CHR16: 89894906 -89937727
Locus: 16q24.3
Gene Diseases
The TCF25 SPIRE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Breast Invasive Carcinoma |
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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