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TEAD1-PARVA Fusion FISH Probe

The TEAD1-PARVA Fusion FISH Probe is used to confirm a fusion of the TEAD1 and PARVA genes. The fusion of the TEAD1 and PARVA genes has been associated with Breast Invasive Carcinoma, Breast Invasive Carcinoma, and Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TEAD1-PARVA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TEAD1-PARVA-20-RERE 20 (40 μL) 200 μL
TEAD1-PARVA-20-REOR 20 (40 μL) 200 μL
TEAD1-PARVA-20-REGO 20 (40 μL) 200 μL
TEAD1-PARVA-20-REGR 20 (40 μL) 200 μL
TEAD1-PARVA-20-REAQ 20 (40 μL) 200 μL
TEAD1-PARVA-20-ORRE 20 (40 μL) 200 μL
TEAD1-PARVA-20-OROR 20 (40 μL) 200 μL
TEAD1-PARVA-20-ORGO 20 (40 μL) 200 μL
TEAD1-PARVA-20-ORAQ 20 (40 μL) 200 μL
TEAD1-PARVA-20-GORE 20 (40 μL) 200 μL
TEAD1-PARVA-20-GOOR 20 (40 μL) 200 μL
TEAD1-PARVA-20-GOGO 20 (40 μL) 200 μL
TEAD1-PARVA-20-GOGR 20 (40 μL) 200 μL
TEAD1-PARVA-20-GOAQ 20 (40 μL) 200 μL
TEAD1-PARVA-20-GRRE 20 (40 μL) 200 μL
TEAD1-PARVA-20-GROR 20 (40 μL) 200 μL
TEAD1-PARVA-20-GRGO 20 (40 μL) 200 μL
TEAD1-PARVA-20-GRGR 20 (40 μL) 200 μL
TEAD1-PARVA-20-GRAQ 20 (40 μL) 200 μL
TEAD1-PARVA-20-AQRE 20 (40 μL) 200 μL
TEAD1-PARVA-20-AQOR 20 (40 μL) 200 μL
TEAD1-PARVA-20-AQGO 20 (40 μL) 200 μL
TEAD1-PARVA-20-AQGR 20 (40 μL) 200 μL
TEAD1-PARVA-20-AQAQ 20 (40 μL) 200 μL

TEAD1 Gene Summary

This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified. [provided by RefSeq, May 2010]

Gene Name: TEA Domain Transcription Factor 1

Chromosome: CHR11: 12695968 -12966284

Locus: 11p15.3

PARVA Gene Summary

This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

Gene Name: Parvin Alpha

Chromosome: CHR11: 12399025 -12556903

Locus: 11p15.3

Gene Diseases

The TEAD1 PARVA Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma
Breast Invasive Carcinoma
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.