TECPR2-WDR20 Fusion FISH Probe
The TECPR2-WDR20 Fusion FISH Probe is used to confirm a fusion of the TECPR2 and WDR20 genes. The fusion of the TECPR2 and WDR20 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TECPR2-WDR20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-RERE | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-REOR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-REGO | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-REGR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-REAQ | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-ORRE | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-OROR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-ORGO | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-ORAQ | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GORE | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GOOR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GOGO | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GOGR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GOAQ | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GRRE | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GROR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GRGO | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GRGR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-GRAQ | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-AQRE | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-AQOR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-AQGO | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-AQGR | 20 (40 μL) | 200 μL |
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| TECPR2-WDR20-20-AQAQ | 20 (40 μL) | 200 μL |
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TECPR2 Gene Summary
The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Name: Tectonin Beta-propeller Repeat Containing 2
Chromosome: CHR14: 102829299 -102968818
Locus: 14q32.31
WDR20 Gene Summary
This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Name: WD Repeat Domain 20
Chromosome: CHR14: 102606188 -102690010
Locus: 14q32.31
Gene Diseases
The TECPR2 WDR20 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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