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TFEB-MDFI Fusion FISH Probe

The TFEB-MDFI Fusion FISH Probe is used to confirm a fusion of the TFEB and MDFI genes. The fusion of the TFEB and MDFI genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TFEB-MDFI-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TFEB-MDFI-20-RERE 20 (40 μL) 200 μL
TFEB-MDFI-20-REOR 20 (40 μL) 200 μL
TFEB-MDFI-20-REGO 20 (40 μL) 200 μL
TFEB-MDFI-20-REGR 20 (40 μL) 200 μL
TFEB-MDFI-20-REAQ 20 (40 μL) 200 μL
TFEB-MDFI-20-ORRE 20 (40 μL) 200 μL
TFEB-MDFI-20-OROR 20 (40 μL) 200 μL
TFEB-MDFI-20-ORGO 20 (40 μL) 200 μL
TFEB-MDFI-20-ORAQ 20 (40 μL) 200 μL
TFEB-MDFI-20-GORE 20 (40 μL) 200 μL
TFEB-MDFI-20-GOOR 20 (40 μL) 200 μL
TFEB-MDFI-20-GOGO 20 (40 μL) 200 μL
TFEB-MDFI-20-GOGR 20 (40 μL) 200 μL
TFEB-MDFI-20-GOAQ 20 (40 μL) 200 μL
TFEB-MDFI-20-GRRE 20 (40 μL) 200 μL
TFEB-MDFI-20-GROR 20 (40 μL) 200 μL
TFEB-MDFI-20-GRGO 20 (40 μL) 200 μL
TFEB-MDFI-20-GRGR 20 (40 μL) 200 μL
TFEB-MDFI-20-GRAQ 20 (40 μL) 200 μL
TFEB-MDFI-20-AQRE 20 (40 μL) 200 μL
TFEB-MDFI-20-AQOR 20 (40 μL) 200 μL
TFEB-MDFI-20-AQGO 20 (40 μL) 200 μL
TFEB-MDFI-20-AQGR 20 (40 μL) 200 μL
TFEB-MDFI-20-AQAQ 20 (40 μL) 200 μL

MDFI Gene Summary

This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. [provided by RefSeq, Jul 2008]

Gene Name: MyoD Family Inhibitor

Chromosome: CHR6: 41606194 -41621982

Locus: 6p21.1

TFEB Gene Summary

The Transcription Factor EB (TFEB) gene is located on chr6 :41651715-41703997 at 6p21.1.

Gene Name: Transcription Factor EB

Chromosome: CHR6: 41651715 -41703997

Locus: 6p21.1

Gene Diseases

The TFEB MDFI Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.