TGFBRAP1-DPP10 Fusion FISH Probe
The TGFBRAP1-DPP10 Fusion FISH Probe is used to confirm a fusion of the TGFBRAP1 and DPP10 genes. The fusion of the TGFBRAP1 and DPP10 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TGFBRAP1-DPP10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-RERE | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-REOR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-REGO | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-REGR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-REAQ | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-ORRE | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-OROR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-ORGO | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-ORAQ | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GORE | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GOOR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GOGO | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GOGR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GOAQ | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GRRE | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GROR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GRGO | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GRGR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-GRAQ | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-AQRE | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-AQOR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-AQGO | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-AQGR | 20 (40 μL) | 200 μL |
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| TGFBRAP1-DPP10-20-AQAQ | 20 (40 μL) | 200 μL |
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TGFBRAP1 Gene Summary
This gene encodes a protein that binds to transforming growth factor-beta (TGF-beta) receptors and plays a role in TGF-beta signaling. The encoded protein acts as a chaprone in signaling downstream of TGF-beta. It is involved in signal-dependent association with SMAD4. The protein is also a component of mammalian CORVET, a multisubunit tethering protein complex that is involved in fusion of early endosomes. [provided by RefSeq, Jun 2016]
Gene Name: Transforming Growth Factor Beta Receptor Associated Protein 1
Chromosome: CHR2: 105883539 -105946148
Locus: 2q12.1-q12.2
DPP10 Gene Summary
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Dipeptidyl Peptidase Like 10
Chromosome: CHR2: 115199898 -116602326
Locus: 2q14.1
Gene Diseases
The TGFBRAP1 DPP10 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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