THBS1-AGBL1 Fusion FISH Probe
The THBS1-AGBL1 Fusion FISH Probe is used to confirm a fusion of the THBS1 and AGBL1 genes. The fusion of the THBS1 and AGBL1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| THBS1-AGBL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-RERE | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-REOR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-REGO | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-REGR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-REAQ | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-ORRE | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-OROR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-ORGO | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GORE | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GOOR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GOGO | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GOGR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GRRE | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GROR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GRGO | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GRGR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-AQRE | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-AQOR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-AQGO | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-AQGR | 20 (40 μL) | 200 μL |
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| THBS1-AGBL1-20-AQAQ | 20 (40 μL) | 200 μL |
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THBS1 Gene Summary
The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
Gene Name: Thrombospondin 1
Chromosome: CHR15: 39873279 -39889668
Locus: 15q14
AGBL1 Gene Summary
Polyglutamylation is a reversible posttranslational modification catalyzed by polyglutamylases that results in the addition of glutamate side chains on the modified protein. This gene encodes a glutamate decarboxylase that catalyzes the deglutamylation of polyglutamylated proteins. Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy. [provided by RefSeq, Nov 2013]
Gene Name: ATP/GTP Binding Protein Like 1
Chromosome: CHR15: 86685241 -87572283
Locus: 15q25.3
Gene Diseases
The THBS1 AGBL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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