THOC1-GLI3 Fusion FISH Probe
The THOC1-GLI3 Fusion FISH Probe is used to confirm a fusion of the THOC1 and GLI3 genes. The fusion of the THOC1 and GLI3 genes has been associated with Sarcoma, and Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| THOC1-GLI3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-RERE | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-REOR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-REGO | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-REGR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-REAQ | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-ORRE | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-OROR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-ORGO | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-ORAQ | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GORE | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GOOR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GOGO | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GOGR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GOAQ | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GRRE | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GROR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GRGO | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GRGR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-GRAQ | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-AQRE | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-AQOR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-AQGO | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-AQGR | 20 (40 μL) | 200 μL |
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| THOC1-GLI3-20-AQAQ | 20 (40 μL) | 200 μL |
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GLI3 Gene Summary
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Gene Name: GLI Family Zinc Finger 3
Chromosome: CHR7: 42000547 -42276618
Locus: 7p14.1
THOC1 Gene Summary
HPR1 is part of the TREX (transcription/export) complex, which includes TEX1 (MIM 606929), THO2 (MIM 300395), ALY (MIM 604171), and UAP56 (MIM 142560).[supplied by OMIM, Nov 2010]
Gene Name: THO Complex 1
Chromosome: CHR18: 214519 -268059
Locus: 18p11.32
Gene Diseases
The THOC1 GLI3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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