SEARCH OUR PRODUCT CATALOG

TIA1-ACTR2 Fusion FISH Probe

The TIA1-ACTR2 Fusion FISH Probe is used to confirm a fusion of the TIA1 and ACTR2 genes. The fusion of the TIA1 and ACTR2 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TIA1-ACTR2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TIA1-ACTR2-20-RERE 20 (40 μL) 200 μL
TIA1-ACTR2-20-REOR 20 (40 μL) 200 μL
TIA1-ACTR2-20-REGO 20 (40 μL) 200 μL
TIA1-ACTR2-20-REGR 20 (40 μL) 200 μL
TIA1-ACTR2-20-REAQ 20 (40 μL) 200 μL
TIA1-ACTR2-20-ORRE 20 (40 μL) 200 μL
TIA1-ACTR2-20-OROR 20 (40 μL) 200 μL
TIA1-ACTR2-20-ORGO 20 (40 μL) 200 μL
TIA1-ACTR2-20-ORAQ 20 (40 μL) 200 μL
TIA1-ACTR2-20-GORE 20 (40 μL) 200 μL
TIA1-ACTR2-20-GOOR 20 (40 μL) 200 μL
TIA1-ACTR2-20-GOGO 20 (40 μL) 200 μL
TIA1-ACTR2-20-GOGR 20 (40 μL) 200 μL
TIA1-ACTR2-20-GOAQ 20 (40 μL) 200 μL
TIA1-ACTR2-20-GRRE 20 (40 μL) 200 μL
TIA1-ACTR2-20-GROR 20 (40 μL) 200 μL
TIA1-ACTR2-20-GRGO 20 (40 μL) 200 μL
TIA1-ACTR2-20-GRGR 20 (40 μL) 200 μL
TIA1-ACTR2-20-GRAQ 20 (40 μL) 200 μL
TIA1-ACTR2-20-AQRE 20 (40 μL) 200 μL
TIA1-ACTR2-20-AQOR 20 (40 μL) 200 μL
TIA1-ACTR2-20-AQGO 20 (40 μL) 200 μL
TIA1-ACTR2-20-AQGR 20 (40 μL) 200 μL
TIA1-ACTR2-20-AQAQ 20 (40 μL) 200 μL

TIA1 Gene Summary

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]

Gene Name: TIA1 Cytotoxic Granule Associated RNA Binding Protein

Chromosome: CHR2: 70436575 -70475779

Locus: 2p13.3

ACTR2 Gene Summary

The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: ARP2 Actin Related Protein 2 Homolog

Chromosome: CHR2: 65454828 -65498390

Locus: 2p14

Gene Diseases

The TIA1 ACTR2 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.