TJP1-SLC20A1 Fusion FISH Probe
The TJP1-SLC20A1 Fusion FISH Probe is used to confirm a fusion of the TJP1 and SLC20A1 genes. The fusion of the TJP1 and SLC20A1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TJP1-SLC20A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-RERE | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-REOR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-REGO | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-REGR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-REAQ | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-ORRE | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-OROR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-ORGO | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GORE | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GOOR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GOGO | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GOGR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GRRE | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GROR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GRGO | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GRGR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-AQRE | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-AQOR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-AQGO | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-AQGR | 20 (40 μL) | 200 μL |
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| TJP1-SLC20A1-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC20A1 Gene Summary
The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.[provided by RefSeq, Mar 2011]
Gene Name: Solute Carrier Family 20 Member 1
Chromosome: CHR2: 113403433 -113421400
Locus: 2q14.1
TJP1 Gene Summary
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Gene Name: Tight Junction Protein 1
Chromosome: CHR15: 29992356 -30114706
Locus: 15q13.1
Gene Diseases
The TJP1 SLC20A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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