TLK1-ADK Fusion FISH Probe
The TLK1-ADK Fusion FISH Probe is used to confirm a fusion of the TLK1 and ADK genes. The fusion of the TLK1 and ADK genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TLK1-ADK-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-RERE | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-REOR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-REGO | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-REGR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-REAQ | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-ORRE | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-OROR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-ORGO | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-ORAQ | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GORE | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GOOR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GOGO | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GOGR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GOAQ | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GRRE | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GROR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GRGO | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GRGR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-GRAQ | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-AQRE | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-AQOR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-AQGO | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-AQGR | 20 (40 μL) | 200 μL |
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| TLK1-ADK-20-AQAQ | 20 (40 μL) | 200 μL |
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ADK Gene Summary
This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Name: Adenosine Kinase
Chromosome: CHR10: 75910942 -76469061
Locus: 10q11-q24
TLK1 Gene Summary
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Tousled Like Kinase 1
Chromosome: CHR2: 171847332 -172087824
Locus: 2q31.1
Gene Diseases
The TLK1 ADK Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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