TM2D2-ADAM9 Fusion FISH Probe
The TM2D2-ADAM9 Fusion FISH Probe is used to confirm a fusion of the TM2D2 and ADAM9 genes. The fusion of the TM2D2 and ADAM9 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TM2D2-ADAM9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-RERE | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-REOR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-REGO | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-REGR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-REAQ | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-ORRE | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-OROR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-ORGO | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-ORAQ | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GORE | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GOOR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GOGO | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GOGR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GOAQ | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GRRE | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GROR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GRGO | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GRGR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-GRAQ | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-AQRE | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-AQOR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-AQGO | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-AQGR | 20 (40 μL) | 200 μL |
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| TM2D2-ADAM9-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAM9 Gene Summary
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
Gene Name: ADAM Metallopeptidase Domain 9
Chromosome: CHR8: 38854504 -38962779
Locus: 8p11.22
TM2D2 Gene Summary
The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. This gene has multiple alternatively spliced transcript variants which encode two different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: TM2 Domain Containing 2
Chromosome: CHR8: 38846326 -38854041
Locus: 8p11.22
Gene Diseases
The TM2D2 ADAM9 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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