TM2D2-IDO2 Fusion FISH Probe
The TM2D2-IDO2 Fusion FISH Probe is used to confirm a fusion of the TM2D2 and IDO2 genes. The fusion of the TM2D2 and IDO2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TM2D2-IDO2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-RERE | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-REOR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-REGO | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-REGR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-REAQ | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-ORRE | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-OROR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-ORGO | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GORE | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GOOR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GOGO | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GOGR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GRRE | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GROR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GRGO | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GRGR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-AQRE | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-AQOR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-AQGO | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-AQGR | 20 (40 μL) | 200 μL |
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| TM2D2-IDO2-20-AQAQ | 20 (40 μL) | 200 μL |
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TM2D2 Gene Summary
The protein encoded by this gene contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily. This protein has sequence and structural similarities to the beta-amyloid binding protein (BBP), but, unlike BBP, it does not regulate a response to beta-amyloid peptide. This protein may have regulatory roles in cell death or proliferation signal cascades. This gene has multiple alternatively spliced transcript variants which encode two different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: TM2 Domain Containing 2
Chromosome: CHR8: 38846326 -38854041
Locus: 8p11.22
IDO2 Gene Summary
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
Gene Name: Indoleamine 2,3-dioxygenase 2
Chromosome: CHR8: 39792473 -39873910
Locus: 8p11.21
Gene Diseases
The TM2D2 IDO2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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