TMBIM6-TYK2 Fusion FISH Probe
The TMBIM6-TYK2 Fusion FISH Probe is used to confirm a fusion of the TMBIM6 and TYK2 genes. The fusion of the TMBIM6 and TYK2 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMBIM6-TYK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-RERE | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-REOR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-REGO | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-REGR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-REAQ | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-ORRE | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-OROR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-ORGO | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GORE | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GOOR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GOGO | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GOGR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GRRE | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GROR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GRGO | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GRGR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-AQRE | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-AQOR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-AQGO | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-AQGR | 20 (40 μL) | 200 μL |
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| TMBIM6-TYK2-20-AQAQ | 20 (40 μL) | 200 μL |
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TMBIM6 Gene Summary
The Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6) gene is located on chr12 :50135292-50158717 at 12q13.12.
Gene Name: Transmembrane BAX Inhibitor Motif Containing 6
Chromosome: CHR12: 50135292 -50158717
Locus: 12q13.12
TYK2 Gene Summary
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine Kinase 2
Chromosome: CHR19: 10461203 -10491248
Locus: 19p13.2
Gene Diseases
The TMBIM6 TYK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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