TMEM120B-UBTF Fusion FISH Probe
The TMEM120B-UBTF Fusion FISH Probe is used to confirm a fusion of the TMEM120B and UBTF genes. The fusion of the TMEM120B and UBTF genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM120B-UBTF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM120B-UBTF-20-AQAQ | 20 (40 μL) | 200 μL |
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UBTF Gene Summary
This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
Gene Name: Upstream Binding Transcription Factor, RNA Polymerase I
Chromosome: CHR17: 42282400 -42298994
Locus: 17q21.31
TMEM120B Gene Summary
The Transmembrane Protein 120B (TMEM120B) gene is located on chr12 :122150657-122219974 at 12q24.31.
Gene Name: Transmembrane Protein 120B
Chromosome: CHR12: 122150657 -122219974
Locus: 12q24.31
Gene Diseases
The TMEM120B UBTF Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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