TMEM123-CNTN5 Fusion FISH Probe
The TMEM123-CNTN5 Fusion FISH Probe is used to confirm a fusion of the TMEM123 and CNTN5 genes. The fusion of the TMEM123 and CNTN5 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM123-CNTN5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM123-CNTN5-20-AQAQ | 20 (40 μL) | 200 μL |
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CNTN5 Gene Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Contactin 5
Chromosome: CHR11: 98891705 -100229616
Locus: 11q22.1
TMEM123 Gene Summary
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq, Jul 2008]
Gene Name: Transmembrane Protein 123
Chromosome: CHR11: 102267055 -102323775
Locus: 11q22.2
Gene Diseases
The TMEM123 CNTN5 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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