TMEM131-PLA2G6 Fusion FISH Probe
The TMEM131-PLA2G6 Fusion FISH Probe is used to confirm a fusion of the TMEM131 and PLA2G6 genes. The fusion of the TMEM131 and PLA2G6 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM131-PLA2G6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM131-PLA2G6-20-AQAQ | 20 (40 μL) | 200 μL |
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PLA2G6 Gene Summary
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
Gene Name: Phospholipase A2 Group VI
Chromosome: CHR22: 38507501 -38577836
Locus: 22q13.1
TMEM131 Gene Summary
The Transmembrane Protein 131 (TMEM131) gene is located on chr2 :98372800-98612354 at 2q11.2.
Gene Name: Transmembrane Protein 131
Chromosome: CHR2: 98372800 -98612354
Locus: 2q11.2
Gene Diseases
The TMEM131 PLA2G6 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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