TMEM135-GRM5 Fusion FISH Probe
The TMEM135-GRM5 Fusion FISH Probe is used to confirm a fusion of the TMEM135 and GRM5 genes. The fusion of the TMEM135 and GRM5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM135-GRM5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM135-GRM5-20-AQAQ | 20 (40 μL) | 200 μL |
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GRM5 Gene Summary
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: Glutamate Metabotropic Receptor 5
Chromosome: CHR11: 88237743 -88796816
Locus: 11q14.2-q14.3
TMEM135 Gene Summary
The Transmembrane Protein 135 (TMEM135) gene is located on chr11 :86748885-87039876 at 11q14.2.
Gene Name: Transmembrane Protein 135
Chromosome: CHR11: 86748885 -87039876
Locus: 11q14.2
Gene Diseases
The TMEM135 GRM5 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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