TMEM150C-SCD5 Fusion FISH Probe
The TMEM150C-SCD5 Fusion FISH Probe is used to confirm a fusion of the TMEM150C and SCD5 genes. The fusion of the TMEM150C and SCD5 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM150C-SCD5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM150C-SCD5-20-AQAQ | 20 (40 μL) | 200 μL |
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SCD5 Gene Summary
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM, Mar 2008]
Gene Name: Stearoyl-CoA Desaturase 5
Chromosome: CHR4: 83550689 -83720010
Locus: 4q21.22
TMEM150C Gene Summary
This gene encodes a transmembrane protein component of a mechanosensitve ion channel that is activated by mechanical stimuli in various cell types and confers slowly adapting, mechanically activated currents in dorsal root ganglion neurons. Mechanically activated ion channels are sensors that are critical for hearing, touch, pain, and blood pressure regulation. [provided by RefSeq, Jul 2017]
Gene Name: Transmembrane Protein 150C
Chromosome: CHR4: 83405603 -83483126
Locus: 4q21.22
Gene Diseases
The TMEM150C SCD5 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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