TMEM50B-GART Fusion FISH Probe
The TMEM50B-GART Fusion FISH Probe is used to confirm a fusion of the TMEM50B and GART genes. The fusion of the TMEM50B and GART genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM50B-GART-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM50B-GART-20-AQAQ | 20 (40 μL) | 200 μL |
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TMEM50B Gene Summary
The Transmembrane Protein 50B (TMEM50B) gene is located on chr21 :34804792-34852316 at 21q22.11.
Gene Name: Transmembrane Protein 50B
Chromosome: CHR21: 34804792 -34852316
Locus: 21q22.11
GART Gene Summary
The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Phosphoribosylglycinamide Formyltransferase, Phosphoribosylglycinamide Synthetase, Phosphoribosylaminoimidazole Synthetase
Chromosome: CHR21: 34876237 -34915198
Locus: 21q22.11
Gene Diseases
The TMEM50B GART Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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