TMEM87B-IL1RN Fusion FISH Probe
The TMEM87B-IL1RN Fusion FISH Probe is used to confirm a fusion of the TMEM87B and IL1RN genes. The fusion of the TMEM87B and IL1RN genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMEM87B-IL1RN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-RERE | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-REOR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-REGO | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-REGR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-REAQ | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-ORRE | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-OROR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-ORGO | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GORE | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GOOR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GOGO | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GOGR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GRRE | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GROR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GRGO | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GRGR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-AQRE | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-AQOR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-AQGO | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-AQGR | 20 (40 μL) | 200 μL |
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| TMEM87B-IL1RN-20-AQAQ | 20 (40 μL) | 200 μL |
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IL1RN Gene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016]
Gene Name: Interleukin 1 Receptor Antagonist
Chromosome: CHR2: 113875469 -113891593
Locus: 2q14.1
TMEM87B Gene Summary
This gene encodes a protein that may interact with human papillomavirus type 18 E6 oncogene. The protein is also likely to be involved in endosome-to-trans-Golgi network retrograde transport. The gene is expressed in adult and fetal tissues, including brain and heart. This gene is a component of the 2q13 deletion syndrome. Mutations in this gene may be associated with congenital heart defects. [provided by RefSeq, Aug 2016]
Gene Name: Transmembrane Protein 87B
Chromosome: CHR2: 112812799 -112876895
Locus: 2q13
Gene Diseases
The TMEM87B IL1RN Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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