TMLHE-CDK12 Fusion FISH Probe
The TMLHE-CDK12 Fusion FISH Probe is used to confirm a fusion of the TMLHE and CDK12 genes. The fusion of the TMLHE and CDK12 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TMLHE-CDK12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-RERE | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-REOR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-REGO | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-REGR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-REAQ | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-ORRE | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-OROR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-ORGO | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-ORAQ | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GORE | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GOOR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GOGO | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GOGR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GOAQ | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GRRE | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GROR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GRGO | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GRGR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-GRAQ | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-AQRE | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-AQOR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-AQGO | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-AQGR | 20 (40 μL) | 200 μL |
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| TMLHE-CDK12-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK12 Gene Summary
The Cyclin Dependent Kinase 12 (CDK12) gene is located on chr17 :37617738-37690800 at 17q12.
Gene Name: Cyclin Dependent Kinase 12
Chromosome: CHR17: 37617738 -37690800
Locus: 17q12
TMLHE Gene Summary
This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Trimethyllysine Hydroxylase, Epsilon
Chromosome: CHRX: 154718672 -154842622
Locus: Xq28
Gene Diseases
The TMLHE CDK12 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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