TMLHE-NEDD9 Fusion FISH Probe
The TMLHE-NEDD9 Fusion FISH Probe is used to confirm a fusion of the TMLHE and NEDD9 genes. The fusion of the TMLHE and NEDD9 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMLHE-NEDD9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TMLHE-NEDD9-20-AQAQ | 20 (40 μL) | 200 μL |
|
NEDD9 Gene Summary
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Name: Neural Precursor Cell Expressed, Developmentally Down-regulated 9
Chromosome: CHR6: 11183530 -11382581
Locus: 6p24.2
TMLHE Gene Summary
This gene encodes the protein trimethyllysine dioxygenase which is the first enzyme in the carnitine biosynthesis pathway. Carnitine play an essential role in the transport of activated fatty acids across the inner mitochondrial membrane. The encoded protein converts trimethyllysine into hydroxytrimethyllysine. A pseudogene of this gene is found on chromosome X. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Name: Trimethyllysine Hydroxylase, Epsilon
Chromosome: CHRX: 154718672 -154842622
Locus: Xq28
Gene Diseases
The TMLHE NEDD9 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|